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Friday, February 15, 2008

Vasculitis including Temporal Arteritis

What is Vasculitis including Temporal Arteritis?
Vasculitis is an inflammation of the vascular system, which includes the veins, arteries, and capillaries. Dysfunction may occur due to the inflammation itself or over time as the blood vessel walls swell, harden, thicken, and develop scar tissue. This narrows the passage through which blood can flow. As the condition progresses, it can slow or completely stop the normal flow of blood. Vasculitis can cause problems in any organ system, including the central (CNS) and peripheral (PNS) nervous systems. A vasculitis syndrome may begin suddenly or develop over time. Symptoms include headaches, fever, malaise (feeling out-of-sorts), rapid weight loss, confusion or forgetfulness, aches and pains in the joints and muscles, pain while chewing or swallowing, paralysis or numbness in the arms or legs, double vision, blurred vision, or blindness.
Although these disorders are rare, there are many of them. Some of the better understood syndromes are temporal arteritis (also called giant cell arteritis or cranial arteritis), primary angiitis of the CNS (granulomatous angiitis), Takayasu's disease, and periarteritis nodosa. The diagnosis of a specific CNS or PNS vasculitis disorder will depend upon the number of blood vessels involved, their size, and their location in the CNS or PNS.
Is there any treatment?
The standard treatment for these disorders is varying doses of steroids such as prednisone and methylprednisolone, along with immunosuppressive drugs such as cyclophosphamide and low-dose methotrexate. Individuals must be carefully monitored. Long-term use of steroids can cause harmful side effects such as collapsing vertebrae, muscle pain, diabetes, and cataracts. The use of immunosuppressive drugs makes people more susceptible to infectious diseases such as influenza and pneumonia.
What is the prognosis?
The prognosis is dependent upon the specific vasculitis syndrome and whether treatment has been begun early enough. With early treatment, the course of temporal arteritis, for example, is usually limited to one to two years and is rarely fatal. On the other hand, untreated periarteritis nodosa is often fatal, ending in heart failure, kidney failure, or the failure of other vital organs. Most people will respond well to steroids and immunosuppressive drugs.

2 comments:

Unknown said...

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Unknown said...

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Luckily, everything seemed to be okay after she took an Herbal Medicine. I wish I could say that’s the end of it because she havn't had any symptoms since then.
Having a child with special needs is difficult. You sit living in fear of the reality your child may face, never really knowing what will happen until it does. Do not expose yourself to more danger, use a herbal remedy that is safe and effective. If interested contact him:
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